seekRNA provides a new route for precise gene editing

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Features of the IS1111 and IS110 family. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49474-9 Scientists at the University of Sydney have developed a gene-editing tool with greater precision and flexibility than the industry standard, CRISPR, which has revolutionized genetic engineering in medicine, agriculture and biotechnology. SeekRNA uses a programmable ribonucleic acid (RNA) array that can directly … Read more

The 2025 Social Security cost of living adjustment (COLA) is on track to do something that hasn’t happened in 28 years

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In May, 51 million retiree beneficiaries took home an average Social Security check totaling $1,916.63, up $23,000 on an annualized basis. While that may not sound like a game-changing sum of money, the average retiree would struggle mightily without their guaranteed monthly benefit. For the past 23 years, the national Gallup poll has surveyed retirees … Read more

JWST observations reveal a mature quasar at cosmic dawn

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Artist’s impression of the bright core region of a quasar, an active galaxy. The supermassive black hole at the center is surrounded by a bright disk of gas and dust. The dust component can further obscure the view of the interior and shines primarily in the mid-infrared, light that can be analyzed by the James … Read more

Horror games like Still Wakes The Deep

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Main points Still Wakes The Deep takes inspiration from other survival horror titles to focus on narrative and atmosphere over combat. Critics praise the game’s beautiful graphics and compelling story, but note its linearity and similarities to other survival horrors. Setting the game on an oil rig evokes Lovecraftian terror, similar to other horror games … Read more

US’s busiest transit hub hit by delays as infrastructure breakdowns hit during heat wave

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Extreme heat coupled with strained infrastructure, malfunctions and mechanical problems at Amtrak and New Jersey Transit brought agony and massive delays to tens of thousands of commuters across the Northeast this week. Rail service between New Jersey and New York’s Penn Station was suspended Thursday before the evening commute and again Friday morning, with Citing … Read more

Same-sex behavior between animals is becoming less reported, study finds

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Sign up for CNN’s Science of Miracles newsletter. Explore the universe with news of fascinating discoveries, scientific advances and more. CNN – Same-sex sexual behavior has been observed in more than 1,500 animal species, but a new study has found that it is massively underreported by researchers. Observations of this same-sex behavior in animals, such … Read more

Shadow Of The Erdtree’ In ‘mixed’ reviews because it’s so hard

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Knight of Blackgoal The Elden ring FromSoft games are extremely difficult. The first Elden ring had many areas and very difficult fights. But it seems that Shadow of the Erdtree may have broken a significant number of players, even long-time veterans. I was actually quite surprised to see this, given that most players gave FromSoft … Read more

The 2025 Social Security cost of living adjustment (COLA) is on track to do something that hasn’t happened in 28 years

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Even a rare Social Security cost-of-living adjustment (COLA) may not stop seniors from getting the short end of the stick, once again. In May, 51 million retiree beneficiaries took home an average Social Security check totaling $1,916.63, up $23,000 on an annualized basis. While that may not sound like a game-changing sum of money, the … Read more

Study of C. elegans reveals that mRNA balance in cells affects lifespan

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Composite image showing fluorescently labeled nuclei in each cell of five different C. elegans captured at the Advanced Light Microscopy Unit at CRG. Credit: Jeremy Vicencio, Nadia Halidi/Centro de Regulación Genómica Why do some people live longer than others? The genes in our DNA sequence are important, helping to avoid disease or maintain overall health, … Read more

Zelda: Echoes of Wisdom confirms that Zelda games have changed forever

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The biggest shock of Tuesday The Legend of Zelda: Echoes of Wisdom revealed, of course, that Princess Zelda will be the playable protagonist. The second biggest shock was that the game exists at all, and that it’s coming out in three months. The third biggest hit took a little longer to register for me, but … Read more